• Are aliquoting services available?

    CPC Scientific can indeed aliquot any order to your specifications. By aliquotting your order into smaller quantities, this service will allow you to store and access your peptide with ease and also gives you the ability to standardize your protocols. Perhaps most important, the peptide will enjoy greater stability in the long run by preventing […]

    Published On: November 2nd, 2019Categories:
  • Will CPC Scientific pool my peptides?

    CPC performs a very specialized pooling service for its customers. We can customize this to suit any customer’s needs, but we have a general protocol that is very effective at demonstrating the contents of a pool. First, subpools of 20 peptides are created. MS is run on these pools to display each peak for each […]

    Published On: November 2nd, 2019Categories:
  • What is the difference between catalog and custom peptides?

    Catalog peptides are commercially available, published sequences. Commonly used catalog peptides are frequently produced in bulk at purities exceeding 95%, and they are generally kept in-stock. Producing these peptides in larger quantities allows companies to sell them at lower prices due to the bulk process involved. Custom peptides, on the other hand, are not public […]

    Published On: November 2nd, 2019Categories:
  • What type of quality control (QC) will be performed on my peptides?

    Every peptide (including crude) is shipped with HPLC and MS. A bonus that CPC provides with its QC package is a recommended solubility test on each peptide. This solubility test utilizes solvents that are applicable for your experiment (water is the first choice), and can be customized according to the customer’s specifications. The test will […]

    Published On: November 2nd, 2019Categories:
  • Are there any limitations on the types of peptides that we can produce?

    CPC Scientific has produced a peptide of 130 amino acids in length, but in general, peptides of more than 30 amino acids can be problematic. Solubility is one of the most important factors to consider when designing a peptide as it will affect the purity attained since HPLC is performed in solution. The more hydrophobic […]

    Published On: November 2nd, 2019Categories:
  • How are peptides synthesized?

    The crucial link in peptide synthesis is the peptides bond formed by condensation of the alpha-amino group of one amino acid and carboxyl group of another amino acid. Amino acids contain a central carbon atom surrounded by hydrogen, an amino group, a carboxyl group, and a side chain group, designated as R. The R group […]

    Published On: November 2nd, 2019Categories:
  • How does CPC Scientific conjugate peptides to carrier proteins for antibody production?

    When producing peptide-antibodies, it is important to use a carrier protein to elicit a better response from the animal. Commonly used carrier proteins are BSA and KLH, with KLH preferred for its higher immunogenicity. Peptides coupled with BSA will generate antibodies against both the peptide and the BSA, which could result in incorrect ELISA readings. […]

    Published On: November 2nd, 2019Categories:
  • What is the difference between gross and net peptide weight?

    All peptides are delivered by gross weight unless otherwise specified. Gross peptide weight is the weight of the peptide and peptide impurities as well as components such as salts, counter ions, residual solvents, and water. Net peptide, on the other hand, is a calculation of merely the peptide present. In certain experiments, this can be […]

    Published On: November 2nd, 2019Categories: