CPC Scientific has produced a peptide of 130 amino acids in length, but in general, peptides of more than 30 amino acids can be problematic. Solubility is one of the most important factors to consider when designing a peptide as it will affect the purity attained since HPLC is performed in solution. The more hydrophobic residues in the sequence, the less soluble the peptide is. Certain sequences can also aggregate which will lead to difficulties in production. CPC has over 100,000 peptides worth of peptide design experience at your disposal, and we are happy to assist any questions.
