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      1. Home
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      3. Citations

      Citations Archive

      • Novel structures of self-associating stapled peptides.

        Bhattacharya, Shibani, et al. Biopolymers 97.5 (2012): 253-264.

        "The stapled peptides with greater than 90% purity were synthesized by.. CPC Scientific, CA"

        Published On: December 14th, 2011Categories: Citations, Stapled Peptides
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      • Single and Combination Herpes Simplex Virus Type 2 Glycoprotein Vaccines Adjuvanted with CpG Oligodeoxynucleotides or Monophosphoryl Lipid A Exhibit Differential Immunity That Is Not Correlated to Protection in Animal Models.

        Khodai, T., Chappell, D., Christy, C., Cockle, P., Eyles, J., Hammond, D., Gore, K., McCluskie, M.J., Evans, D.M., Lang, S. and Loudon, P.T. Clinical and Vaccine Immunology 18, no. 10 (2011): 1702-1709.

        • Vaccines Research Unit, Pfizer Research and Development, Sandwich, United Kingdom

        Peptides (CPC Scientific) representing selected sequences of gD and gB that had previously been demonstrated to contain T cell epitopes (data not shown) were synthesized as 15-mers, quality assessed, and formulated into pools representing each protein.

        Published On: September 1st, 2011Categories: Citations
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      • Design and structure of stapled peptides binding to estrogen receptors.

        Phillips, Chris, et al. Journal of the American Chemical Society 133.25 (2011): 9696-9699.

        "Synthetic peptides that specifically bind nuclear hormone receptors offer an alternative approach to small molecules for the modulation of receptor signaling and subsequent gene expression. [..] Using a number of biophysical techniques, including crystal structure analysis of receptor–stapled peptide complexes, we describe in detail the molecular interactions and demonstrate that all-hydrocarbon staples modulate molecular recognition events."

        Published On: May 25th, 2011Categories: Citations, coauthored, publications, Stapled Peptides
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      • Evolution of cyclic peptide protease inhibitors.

        Young, Travis S., et al. Proceedings of the National Academy of Sciences 108.27 (2011): 11052-11056.

        "To determine the IC50 values of the selected cyclic peptides, we chemically synthesized the peptides C2 and G12 in both linear and cyclic forms (CPC Scientific)."

        Published On: May 23rd, 2011Categories: Citations, Peptide Macrocycles
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      • Scarcity or absence of humoral immune responses in the plasma and cervicovaginal lavage fluids of heavily HIV-1-exposed but persistently seronegative women.

        Mestecky, Jiri, et al. AIDS Research and Human Retroviruses 27.5 (2011): 469-486.

        "The peptides were synthesized as 4-branch MAPS peptides that include a SGGRGG spacer at the C-terminal residue to distance the gp41 sequence from the MAPS (CPC Scientific; San Jose, CA)."

        Published On: May 4th, 2011Categories: Antimicrobial Peptides, Citations
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      • Design and NMR Studies of Cyclic Peptides Targeting the N-Terminal Domain of the Protein Tyrosine Phosphatase YopH.

        Leone, Marilisa, et al. Chemical Biology & Drug Design 77.1 (2011): 12-19.

        "Cyclo-DEYDDPfK; Cyclo-DE(pY)LDPfK; Cyclo-DE(FCOOH)LDPfK (FCOOH= phenylalanine with a carboxyl group at the para position) were purchased either from the MCW facility of the Wisconsin Medical College or from CPC Scientific (San José, CA, USA)"

        Published On: November 30th, 2010Categories: Citations, D-Amino Acids, Peptide Macrocycles, Phosphorylated Peptides, Showcase Phosphorylation
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      • SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1

        Pacholec, M., Bleasdale, J.E., Chrunyk, B., Cunningham, D., Flynn, D., Garofalo, R.S., Griffith, D., Griffor, M., Loulakis, P., Pabst, B. and Qiu, X.Journal of Biological Chemistry 285, no. 11 (2010): 8340-8351.

        • Departments of Cardiovascular, Metabolic and Endocrine Diseases, and Structural Biology, Pfizer Global Research and Development, Groton, Connecticut 06340

        The p53-derived peptides, TAMRA-p53 peptide and native p53 peptide, were custom-synthesized by CPC Scientific.

        Published On: March 1st, 2010Categories: Citations, Dye-Labeled
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      • Electropositive charge in α-defensin bactericidal activity: functional effects of Lys-for-Arg substitutions vary with the peptide primary structure.

        Llenado, R. Alan, et al. Infection and Immunity 77.11 (2009): 5035-5043.

        "(R/K)-RMAD-4 [rhesus myeloid α-defensin 4] [(R1/2/5/7/10/13/14/26/33K)-RMAD-462-94] was custom synthesized by CPC Scientific, Inc. (San Jose, CA) and refolded as described previously…"

        Published On: October 16th, 2009Categories: Antimicrobial Peptides, Citations, Multiple Disulfide Bridges
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      • Transition metal complex cations as reagents for gas-phase transformation of multiply deprotonated polypeptides.

        Crizer, David M., Yu Xia, and Scott A. McLuckey. Journal of the American Society for Mass Spectrometry 20.9 (2009): 1718-1722.

        Phosphopeptide LPISASHpSpSKTR was synthesized by CPC Scientific (San Jose, CA, USA). Both peptides were diluted to a concentration of 20 μM in 49/49/2 (vol/vol/vol) methanol/water/ammonium hydroxide solution."

        Published On: September 5th, 2009Categories: Citations, Phosphorylated Peptides
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      • Characterizing the Effects of the Juxtamembrane Domain on Vascular Endothelial Growth Factor Receptor-2 Enzymatic Activity, Autophosphorylation, and Inhibition by Axitinib.

        Solowiej, J., Bergqvist, S., McTigue, M.A., Marrone, T., Quenzer, T., Cobbs, M., Ryan, K., Kania, R.S., Diehl, W. and Murray, B.W. Biochemistry 48, no. 29 (2009): 7019-7031.

        • Pfizer Global Research and Development, La Jolla, Pfizer Inc., 10777 Science Center Drive, San Diego, California 92121.

        A peptide designed to encompass VEGFR2 residues 786-805 was synthesized and purified to 98% purity (CPC Scientific, San Jose, CA). Compounds were synthesized as described in patents: AG-13736 (35), AG-13974 (36), AG-28038 (35), and AG-28047 (37).

        Published On: June 15th, 2009Categories: Citations
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