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      1. Home
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      3. Citations

      Citations Archive

      • 10E8-like neutralizing antibodies against HIV-1 induced using a precisely designed conformational peptide as a vaccine prime.

        Yu, Yang, et al. Science China Life Sciences 57.1 (2014): 117-127.

        "The peptides, shown in Figure 1, were designed and synthesized. MPER (RRRNEQELLELDKWASLWNWFDITNWLWYIRRRR), TT peptide (FNNFTVSFWLRVPKVSASHLE), T10HE peptide (FNNFTVSFWLRVPKVSASHLE-PEG2-LWNWF-S5-ITN-S5-LWYIR-PEG2-KK), and T10E peptide (FNNFTVSFWLRVPKVSASHLEPEG2-LWNWFDITNWLWYIR-PEG2-KK) were purchased from CPC Scientific Inc. (Sunnyvale, CA, USA)."

        Published On: December 26th, 2013Categories: Citations, PEGylation
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      • Evidence for sequence scrambling and divergent H/D exchange reactions of doubly-charged isobaric b-type fragment ions.

        Zekavat, Behrooz, et al. J. Am. for Mass Spectrometry 25.2 (2014): 226-236.

        "The synthesized cyclo-(RPKPQQFFGL) peptide and human angiotensin II were purchased from CPC Scientific (CPC Scientific Inc., Sunnyvale, CA, USA)."

        Published On: December 18th, 2013Categories: Citations, Peptide Macrocycles
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      • Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit.

        Xu, Y., Cai, T.Q., Castriota, G., Zhou, Y., Hoos, L., Jochnowitz, N., Loewrigkeit, C., Cook, J.A., Wickham, A., Metzger, J.M. and Ogletree, M.L. Thrombosis and Haemostasis 111, no. 04 (2014): 694-704.

        • Departments of Thrombosis, Cardiometabolic Diseases and In Vivo Pharmacology, Merck Research Laboratories, Kenilworth, New Jersey, USA

        CHG-GR-AFC (CPC Scientific, Sunnyvale, CA, USA) was used for rabbit FIXa and FXa, and human activated protein C.

        Published On: December 12th, 2013Categories: Citations, Dye-Labeled
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      • Candida skin test reagent as a novel adjuvant for a human papillomavirus peptide-based therapeutic vaccine.

        Wang, Xuelian, et al. Vaccine 31.49 (2013): 5806-5813.

        “…four current good manufacturing practice-grade HPV16 E6 peptides [E6 1-45, E6 46-80, E6 81-115, and E6 116-158 (referred to as “peptides” hereafter); 10 μg/ml/peptide; made by CPC Scientific, Sunnyvale, CA…”

        Published On: December 2nd, 2013Categories: Citations, GMP Peptide Manufacturing
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      • Dual-acting stapled peptides target both HIV-1 entry and assembly.

        Hongtao Zhang, Francesca Curreli, Abdul A Waheed, Peter Y Mercredi, Mansi Mehta, Pallavi Bhargava, Daniel Scacalossi, Xiaohe Tong, Shawn Lee, Alan Cooper, Michael F Summers, Eric O Freed & Asim K Debnath Retrovirology 10.1 (2013).

        In this report, we expanded the study to i,i+7 hydrocarbon-stapled peptides to delineate their mechanism of action and antiviral activity. We identified three potent inhibitors, NYAD-36, -66 and -67, which showed strong binding to CA in NMR and isothermal titration calorimetry (ITC) studies and disrupted the formation of mature-like particles. They showed typical α-helical structures and penetrated cells; however, the cell penetration was not as efficient as observed with the i,i+4 peptides.

        Published On: November 15th, 2013Categories: Citations, coauthored, publications, Stapled Peptides
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      • Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma.

        Zhen, Eugene Y., Richard E. Higgs, and Jesus A. Gutierrez. Analytical Biochemistry 442.1 (2013): 1-9.

        "Both the stable isotope-labeled (SIL) and unlabeled apelin peptides [apelin-36, apelin-17, apelin-13, (pyr)apelin-13, and apelin-12] were synthesized by CPC Scientific (Sunnyvale, CA, USA)."

        Published On: November 1st, 2013Categories: Citations, Isotope-Labeled Peptides
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      • Discovery of Dap‑3 Polymyxin Analogues for the Treatment of Multidrug-Resistant Gram-Negative Nosocomial Infections.

        Magee, T.V., Brown, M.F., Starr, J.T., Ackley, D.C., Abramite, J.A., Aubrecht, J., Butler, A., Crandon, J.L., Dib-Hajj, F., Flanagan, M.E. and Granskog, K. Journal of Medicinal Chemistry 56, no. 12 (2013): 5079-5093.

        1. Pfizer Worldwide Research & Development, Pfizer, Inc., Groton, Connecticut 06340, United States
        2. CPC Scientific, Hangzhou, P.R. China
        Published On: June 4th, 2013Categories: Citations, coauthored, Peptide Macrocycles, publications, Unnatural Amino Acids
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      • Targeted imaging of esophageal neoplasia with a fluorescently labeled peptide: first-in-human results.

        Sturm, Matthew B., et al. Science Translational Medicine 5.184 (2013): 184ra61-184ra61.

        “For the clinical and pharmacology/toxicology studies, ASY*-FITC was GMP synthesized (CPC Scientific). Stability was evaluated by appearance (color), HPLC, and mass spectrometry for 3 years. The pharmacology/toxicology study in rats was conducted in accordance with FDA CFR title 21, part 58…”

        Published On: May 8th, 2013Categories: Citations, GMP Peptide Manufacturing
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      • Membrane permeability of hydrocarbon-cross-linked peptides.

        Sun, Tzu-Lin, et al. Biophysical Journal 104.9 (2013): 1923-1932.

        "NYAD-1 is H - Ile - Thr - Phe - X - Asp - Leu - Leu - X - Tyr - Tyr - Gly - Pro - NH2 (with special cyclization to get double bond, X = (S) - alpha - (2′-pentenyl)alanine) (4). NYAD-1 and CAI (H-Ile-Thr-Phe-Glu-Asp-Leu-Leu-Asp-Tyr-Tyr-Gly-Pro-NH2) were synthesized by CPC Scientific (San Jose, CA) under the supervision of Xiaohe Tong"

        Published On: May 7th, 2013Categories: Citations, Stapled Peptides
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      • Effects of Chelator Modifications on 68Ga-Labeled [Tyr3] Octreotide Conjugates.

        Lin, Mai, Michael J. Welch, and Suzanne E. Lapi. Molecular Imaging and Biology 15.5 (2013): 606-613.

        "DOTA-[Tyr3]octreotide and NO2A-[Tyr3]octreotide were purchased from CPC Scientific (Sunnyvale, CA)."

        Published On: March 26th, 2013Categories: Citations, Metal Chelates, Peptide Macrocycles
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