"The tandem peptide library used in this work was synthesized via standard FMOC solid-phase peptide synthesis and purified by high-performance liquid chromatography at the MIT Biopolymers Core, Tufts University Core Facility or CPC Scientific, Inc."
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Mac, Quoc D., Anirudh Sivakumar, Hathaichanok Phuengkham, Congmin Xu, James R. Bowen, Fang-Yi Su, Samuel Z. Stentz et al. Nature Biomedical Engineering (2022): 1-15.
"FITC-labelled GzmB substrate peptides with internal quencher ((5FAM)aIEFDSG(K-CPQ2)kkc) were synthesized by CPC Scientific and used for all in vitro activity assays. [..] Quenched fluorescent peptides for screening candidate substrates ((5FAM)-{substrate}-(K-DABCYL)-amide"
Lopez, Andrea, Denis E. Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A. Miranda-Roman, Lars Ulrik Nordstrøm et al. Nature Communications 13, no. 1 (2022): 1-18.
"Hydrocarbon-stapled peptide corresponding to the BH3 domain of BIM, FITC-BIM SAHBA2: FITC-βAla-EIWIAQELRS5IGDS5F’NAYYA-CONH2, where S5 represents the non-natural amino acid inserted for olefin metathesis, was synthesized, purified at >95% purity by CPC Scientific Inc."
Lenz, Morgan R., Shih-Yen Tsai, Anne E. Roessler, Yang Wang, Periannan Sethupathi, W. Keith Jones, Gwendolyn L. Kartje, and William H. Simmons. Journal of Pharmacology and Experimental Therapeutics 380, no. 3 (2022): 220-229.
"The ST-115 [ [(S)-2-mercapto-4-methylpentanoyl]-4(S)-fluoro-Pro-Pro-3(R)-beta-Pro] preparation used in this study was custom synthesized by CPC Scientific, Inc., (Sunnyvale, CA), a GMP-capable company. The synthetic scheme is detailed in US patent"
CPC Scientific would like to officially recognize John Phipps, our Senior Director of Business Development of our West Coast region, as Employee of the Year for 2021! John is being recognized for his outstanding performance in sales, superior dedication, and positive attitude on the job. Thank you, John, for a fantastic 2021!
Cesaro, Angela, Marcelo DT Torres, Rosa Gaglione, Eliana Dell’Olmo, Rocco Di Girolamo, Andrea Bosso, Elio Pizzo et al. ACS Nano 16, no. 2 (2022): 1880-1895.
Expression and isolation of recombinant peptides were carried out as previously described.20 CATH-2 and (ri)-r(P)ApoBSPro peptides were obtained from CPC Scientific Inc. (Sunnyvale, CA) and CASLO ApS (Kongens Lyngby, Denmark), respectively.
SAN JOSE, CA., Dec. 7, 2021/CPCNewswire/ — CPC Scientific Inc. has reached an exciting milestone as the company celebrates 20 years of delivering innovation and service to the peptide industry. Throughout the past two decades, CPC Scientific has provided consistent and quality peptide products to biotechnology and pharmaceutical industries to help bring life-changing therapeutics and […]
Liao, Z., Zhang, C., Ding, L., Moyers, J.S., Tang, J.X. and Beals, J.M. The FEBS Journal 289, no. 9 (2022): 2657-2671.
- Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA.
Synthetic peptides of hIR-B were purchased from CPC Scientific..
Cazanave, S.C., Warren, A.D., Pacula, M., Touti, F., Zagorska, A., Gural, N., Huang, E.K., Sherman, S., Cheema, M., Ibarra, S. and Bates, J. Science Translational Medicine 13, no. 616 (2021): eabe8939.
All peptides were synthesized by CPC Scientific Inc. For fluorogenic assays, peptides were flanked with the fluorophore-quencher pair 5-FAM-CPQ2. For in vivo urine experiments, peptides were barcoded with Glu-Fib–derived and heavy isotope–labeled peptides. PEGylated peptides were pooled prepared before in vivo experiments and stored at 4°C in phosphate-buffered saline.
Diao, J., Komura, R., Sano, T., Pantua, H., Storek, K.M., Inaba, H., Ogawa, H., Noland, C.L., Peng, Y., Gloor, S.L. and Yan, D. Journal of Bacteriology 203, no. 13 (2021): 10-1128.
- Departments of Infectious Diseases, Structural Biology, Biochemical and Cellular Pharmacology, Translational Immunology, Pathology, Protein Chemistry, Early Discovery Biochemistry, Genentech, South San Francisco, California, USA
For the Lgt biochemical assay, the Pal-IAAC and Pal-IAAA peptides were synthesized by CPC Scientific.
