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      1. Home
      2. Tag:
      3. CPQ2

      CPQ2 Archive

      • Magnetite biomineralization in Magnetospirillum magneticum is regulated by a switch-like behavior in the HtrA protease MamE.

        Hershey, David M., et al. BioRxiv (2016): 047555.

        "A custom peptidewith the sequence 5-carboxymethylfluorescein-Thr-Gln-Thr-Val-Ala-Ala-Gly-Ser-Lys(CPQ2)-D-Arg-D-Arg was obtainedcommercially (CPC Scientific)"

        Published On: August 19th, 2016Categories: Citations, D-Amino Acids, Dye-Labeled, FRET Substrates
        Learn More
      • Mathematical framework for activity-based cancer biomarkers.

        Kwong, Gabriel A., et al. Proceedings of the National Academy of Sciences 112.41 (2015): 12627-12632.

        "Cysteine-terminated peptides (Q1 = 5FAM-GGPLGVRGKK(CPQ-2)-PEG2-C, CPC Scientific.."

        Published On: September 28th, 2015Categories: Citations, Dye-Labeled, FRET Substrates, PEGylation
        Learn More
      • FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow.

        Zhu, Shu, et al. Blood 126.12 (2015): 1494-1502.

        "The custom-made thrombin-sensitive peptide azidoacetyl-AK(5FAM)-GALVPRGSAGK(CPQ2)-NH2 was obtained from CPC Scientific (Sunnyvale, CA) for click reactions to anti-CD61, as previously described."

        Published On: September 17th, 2015Categories: Citations, Click Peptides, Dye-Labeled, FRET Substrates, Showcase Click Chemistry, Showcase FRET Peptides, Unnatural Amino Acids
        Learn More
      • Seneca Valley Virus 3C pro Substrate Optimization Yields Efficient Substrates for Use in Peptide-Prodrug Therapy.

        Miles, Linde A., et al. PloS One 10.6 (2015): e0129103.

        "Peptides corresponding to the substrate sequences L/VP4.1 and non-hydrolysable linker (NHL) were synthesized between a 5-carboxyfluorescein (5-FAM) fluorophore/CPC Quencher (CPQ2) quencher pair (CPC Scientific). Additional lysines were added for increased solubility giving final peptide sequences of CPQ2-IVYELQGP-K(5FAM)-KK-NH2 and CPQ2-GGSGGS-K(5FAM)-KK-NH2 for L/VP4.1 and NHL, respectively. The identity and sequence of the L/VP4.1 and NHL peptides were confirmed by CPC Scientific via LC-MS and determined to be 96.7% and 95.1% pure, respectively."

        Published On: June 12th, 2015Categories: Citations, Dye-Labeled, FRET Substrates
        Learn More
      • Identification and Characterization of Fusolisin, the Fusobacterium nucleatum Autotransporter Serine Protease.

        Doron L, Coppenhagen-Glazer S, Ibrahim Y, Eini A, Naor R, Rosen G, Bachrach G. PLoS One. 2014 Oct 30;9(10):e111329.

        "Fusolisin’s restriction specificity was verified using the FRET substrate CPQ2-Gly-Phe-Ile-Thr-Ala-Phe-Pro-Lys-(5FAM)-Arg-Arg-NH2 that was custom synthesized by CPC Scientific (Sunnyvale, CA, USA)."

        Published On: October 1st, 2014Categories: Citations, Dye-Labeled, FRET Substrates
        Learn More
      • Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse.

        Welsh, J. D., et al. Journal of Thrombosis and Haemostasis 10.11 (2012): 2344-2353.

        "Thrombin-sensitive peptide (ThS-P) azidoacetyl alanine-K(5FAM)GALVPRGSAGK(CPQ2) was custom synthesized (2143 MW, > 95% purity; CPC scientific, Sunnyale, CA, USA) and dissolved in DMSO (20 mm ThS-P)."

        Published On: September 15th, 2012Categories: Citations, Click Peptides, Dye-Labeled, FRET Substrates
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