PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM).

SEQUENCE: DPhe-Pro-Arg-CMK

ONE-LETTER SEQUENCE: fPR-CMK

MOLECULAR FORMULA: C₂₁H₃₁ClN₆O₃

MOLECULAR WEIGHT: 450.97

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [71142-71-7]

SYNONYMS: DPhe-Pro-Arg-chloromethylketone

RESEARCH AREA: Thrombin Inhibitor

CATEGORY: Substrate Peptide

REFERENCES:
Arterioscler Thromb Vasc Biol. 2016, 36(3):446-55
J Vasc Surg. 2016, 64(5):1459-1467
J Thromb Haemost. 2011, 9(7):1292-300

SKU(s): THRO-023A, THRO-023B, THRO-023C