Description

This peptide, derived from the latency-associated peptide, inhibits thrombospondin (TSP-1) activation of TGF-beta; thus preventing the progression of hepatic damage and fibrosis.

SEQUENCE: H-Leu-Ser-Lys-Leu-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: LSKL-NH2

MOLECULAR FORMULA: C₂₁H₄₂N₆O₅

MOLECULAR WEIGHT: 458.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [283609-79-0]

SYNONYMS:

RESEARCH AREA: Hematology

REFERENCES:
Ribeiro, SM. et al. J. Biol. Chem. 274, 13586 (1999)
Kondou, H. et al. J. Hepatol. 39, 742 (2003)

SKU(s): THBO-001A

KEYWORDS: