Description

Somatostatin analog DOTA-conjugated for radiolabels such as gallium-67, gallium-68, indium-111, and yttrium-90. This peptide is a useful tool for tumor imaging in radionuclide therapy.

SEQUENCE: DOTA-DPhe-Cys-Tyr-DTrp-Lys-Thr-Cys-Thr-ol (trifluoroacetate salt)
(Cys2 and 7 bridge)

ONE-LETTER SEQUENCE: DOTA-fCYwKTCT-ol (C2&C7 bridge)

MOLECULAR FORMULA: C₆₅H₉₀N₁₄O₁₉S₂

MOLECULAR WEIGHT: 1421.64

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [177943-89-4]

SYNONYMS: DOTA-(Tyr³)-Octreotate, DOTATATE, DOTA-(Tyr³,Thr⁸)-Octreotide, DOTA-[Tyr³] Octreotide Acid (Octreotate)

RESEARCH AREA: Gastrointestinal

REFERENCES:
L.Kolby et al., Br. J. Cancer, 93, 1144 (2005)
R.Valkema et al., J. Nucl. Med., 46, 83S (2005)
M.de Jong et al., J. Nucl. Med., 46, 13S (2005)
W.A.Breeman et al., Eur. J. Nucl. Med. Mol. Imaging, 30, 917 (2003)
A.Capello et al., Cancer Biother. Radiopharm., 18, 761 (2003)
Chinol, M. et al. Semin. Nucl. Med. 32,141(2002)
De Jong, M. et al. Semin Nucl. Med. 32,133(2002)

SKU(s): SOMA-017A, SOMA-017B, SOMA-017C

KEYWORDS: hormone