Description

A group of compounds comprising DOTA, a metal chelator that carries a radionuclide and octreotide (an octapeptide that is a potent somatostatin (SST)) analog (where DOTA is tetra-aza-cyclododecane-N N’N”N-“‘-tetra-acetate).

SEQUENCE: DOTA-DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol (trifluoroacetate salt)
(Cys2 and 7 bridge)

ONE-LETTER SEQUENCE: DOTA-fCFwKTCT-ol (C2&C7 bridge)

MOLECULAR FORMULA: C₆₅H₉₂N₁₄O₁₇S₂

MOLECULAR WEIGHT: 1405.7

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Gastrointestinal

REFERENCES:
L.Kolby et al., Br. J. Cancer, 93, 1144 (2005)
R.Valkema et al., J. Nucl. Med., 46, 83S (2005)
M.de Jong et al., J. Nucl. Med., 46, 13S (2005)
W.A.Breeman et al., Eur. J. Nucl. Med. Mol. Imaging, 30, 917 (2003)
A.Capello et al., Cancer Biother. Radiopharm., 18, 761 (2003)
Chinol, M. et al. Semin. Nucl. Med. 32,141(2002)
De Jong, M. et al. semin Nucl. Med. 32,133(2002)

SKU(s): SOMA-015A, SOMA-015B

KEYWORDS: hormone