Description

Peptide that arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a large precursor, preprosomatostatin. It was found in the central and peripheral nervous system, the gastrointestinal (GI) tract. It additionally increases amylase secretion, cellular cycle GMP, and Ca²⁺ outfluxes.

SEQUENCE: H-Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (trifluoroacetate salt)
(Cys17 and 28 bridge)

ONE-LETTER SEQUENCE: SANSNPAMAPRERKAGCKNFFWKTFTSC (Cys17 and 28 bridge)

MOLECULAR FORMULA: C₁₃₇H₂₀₇N₄₁O₃₉S₃

MOLECULAR WEIGHT: 3148.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [73032-94-7]

SYNONYMS: Somatostatin-28

RESEARCH AREA: Gastrointestinal

REFERENCES:
P. Bohlen et al., BBRC, 96, 725 (1980)
L. Pradayrol, et al., FEBS Letters, 109, 55 (1980)

SKU(s): SOMA-008A, SOMA-008B

KEYWORDS: