Description

The synthetic analog of somatostatin that is three times more potent than the native hormone in inhibiting the secretion of growth hormone.

SEQUENCE: H-DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol (Disulfide Bridge)

ONE-LETTER SEQUENCE: fCFwKTCT-ol (C2&C7 bridge)

MOLECULAR FORMULA: C₄₈H₆₆N₁₀O₉S₂

MOLECULAR WEIGHT: 1019.26

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [79517-01-4]

SYNONYMS: Octreotide, SMS 201-995, (D-Phe⁵,Cys^6,11,D-Trp⁸,L-Threoninol¹²)-Somatostatin-14 (5-12)

RESEARCH AREA: Gastrointestinal

REFERENCES:
S.Grozinsky-Glasberg et al., Neuroendocrinology, 87, 168 (2008)
T.E.Jonassen et al., Am. J. Physiol. Renal Physiol., 291, F537 (2006)
H.G.Ding et al., Chin. Med. J., 117, 913 (2004)
G.Melacini et al., Biochemistry, 36, 1233 (1997)
S.W.Lamberts et al., N. Engl. J. Med., 334, 246 (1996)
D. Maouyo et al., Pancreas, 14, 47 (1997)
W. Bauer et al., Life Sci, 31(11), 1133 (1982)

SKU(s): SOMA-004A, SOMA-004B

KEYWORDS: hormone