Description

The peptide that inhibits the release of the growth hormone thyrotropin and stimulates hormone and prolactin-releasing hormone from the pituitary. It is also the inhibitor of the release of calcitonin, insulin, glucagon, VIP, pancreatic polypeptide, gastrin-releasing peptide, and CCK.

SEQUENCE: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH
(Disulfide Bridge)

ONE-LETTER SEQUENCE: AGCKNFFWKTFTSC (C3&C14 bridge)

MOLECULAR FORMULA: C₇₆H₁₀₄N₁₈O₁₉S₂

MOLECULAR WEIGHT: 1637.9

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [38916-34-6]

SYNONYMS: Somatostatin (1-14), Somatostatin-14, Somatotropin Release-Inhibiting Factor, SRIF, SRIF-14

RESEARCH AREA: Gastrointestinal

REFERENCES:
N.Nestorovic et al., Histochem. Cell Biol., 130, 699 (2008)
D.M.Petrovic-Dergovic et al., Neuropeptides, 41, 485 (2007)
W.van Grondelle et al., J. Struct. Biol., 160, 211 (2007)
G.Scalera, Am. J. Physiol. Regul. Integr. Comp. Physiol., 284, R1389 (2003)
G.Bissette and B.Myers, Life Sci., 51, 1389 (1992)
A.Gomez-Pan and M.D.Rodriguez-Arnao, Clin. Endocrinol. Metab., 12, 469 (1983)
P.Brazeau et al., Science, 179, 77 (1973)

SKU(s): SOMA-001A, SOMA-001B, SOMA-001C

KEYWORDS: hormone