Description

Isotocin (IT) is a biologically active nonapeptide in teleost fish that are produced in neurosecretory neurons in the hypothalamic nuclei. This peptide belongs to the arginine vasopressin-oxytocin family of peptides and has shown to modulate a range of social behaviors.

SEQUENCE: H-Cys-Tyr-Ile-Ser-Asn-Cys-Pro-Ile-Gly-NH2 (trifluoroacetate salt)
(Disulfide bond)

ONE-LETTER SEQUENCE: CYISNCPIG-NH2 (Cys & Cys bridge)

MOLECULAR FORMULA: C₄₁H₆₃N₁₁O₁₂S₂

MOLECULAR WEIGHT: 966.15

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [550-21-0]

SYNONYMS:

RESEARCH AREA: Hormonal

REFERENCES:
Yamashita J, Kawabata Y, Okubo K. J Neuroendocrinol. 2017
Sokołowska, Ewa, Magdalena Gozdowska, and Ewa Kulczykowska. Frontiers in Marine Science 7 (2020): 610.
Ni Y. Feng, Andrew H. Bass, in Hormones, Brain and Behavior (Third Edition), 2017
A. Alunni, … L. Bally-Cuif, in Patterning and Cell Type Specification in the Developing CNS and PNS, 2013

SKU(s): OXYT-004A, OXYT-004B

KEYWORDS: Peptide Macrocycle