Description

An RF-amide peptide ligand for SP9155, an orphan G-protein-coupled receptor with high homology to orexin, neuropeptide FF and CCK receptors. It has been shown to potently activate SP9155 with an EC50 of 7 nM.

SEQUENCE: H-Thr-Ser-Gly-Pro-Leu-Gly-Asn-Leu-Ala-Glu-Glu-Leu-Asn-Gly-Tyr-Ser-Arg-Lys-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: TSGPLGNLAEELNGYSRKKGGFSFRF-NH2

MOLECULAR FORMULA: C₁₂₇H₁₉₅N₃₇O₃₇

MOLECULAR WEIGHT: 2832.17

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [600171-68-4]

SYNONYMS:

RESEARCH AREA: Pain

REFERENCES:
N.Chartrel et al., Proc. Natl. Acad. Sci. USA, 100, 15247 (2003)
Y.Jiang et al., J. Biol. Chem., 278, 27652 (2003)

SKU(s): OPIO-014A, OPIO-014B

KEYWORDS: