Description

Deltorphin, YmFHLMD-amide, a peptide first isolated from skin extracts of the South American frog Phyllomedusa sauvagei, corresponds to the predicted prodermorphin heptapepeptide. Deltorphin acts as a highly potent and fully selective agonist for the delta-opioid receptor.

SEQUENCE: H-Tyr-DMet-Phe-His-Leu-Met-Asp-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Y-DMet-FHLMD-NH2

MOLECULAR FORMULA: C₄₄H₆₂N₁₀O₁₀S₂

MOLECULAR WEIGHT: 955.17

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [119975-64-3]

SYNONYMS:

RESEARCH AREA: Pain

REFERENCES:
M.Amiche et al., Mol. Pharmacol., 35, 774 (1989)
G.Kreil et al., Eur. J. Pharmacol., 162, 123 (1989)
L.H.Lazarus et al., J. Biol. Chem., 264, 3047 (1989)
A.Mor et al., FEBS Lett., 255, 269 (1989)
S.Sagan et al., J. Biol. Chem., 264, 17100 (1989)
P.Melchiorri et al., Eur. J. Pharmacol., 195, 201 (1991)
S.Salvadori et al., J. Med. Chem., 34, 1656 (1991)
L.H.Lazarus et al., J. Med. Chem., 34, 1350 (1991)

SKU(s): OPIO-010A, OPIO-010B

KEYWORDS: