Description

CNP-22 is a potent and selective activator of the human BNP cell surface receptor, a transmembrane guanylyl cyclase.

SEQUENCE: H-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-OH
(Disulfide Bridge)

ONE-LETTER SEQUENCE: GLSKGCFGLKLDRIGSMSGLGC (Disulfide Bridge)

MOLECULAR FORMULA: C₉₃H₁₅₇N₂₇O₂₈S₃

MOLECULAR WEIGHT: 2197.63

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [127869-51-6]

SYNONYMS: CNP-22 (human, porcine, rat), C-Type Natriuretic Peptide (32-53) (human, porcine, rat)

RESEARCH AREA: Cardiovascular

REFERENCES:
W.Xia et al., Proc. Natl. Acad. Sci. USA, 104, 3841 (2007)
S.J.Sangaralingham et al., Am. J. Physiol. Renal Physiol., 301, F943 (2011)
R.Zakeri et al., JACC: Heart Failure, 1, 170 (2013)

SKU(s): NATR-020A, NATR-020B

KEYWORDS: