Description

Brain natriuretic peptide or B-type natriuretic peptide (BNP) (also ventricular natriuretic peptide) is a 32-amino acid peptide secreted by heart ventricles in response to excessive stretching of heart muscle cells (cardiomyocytes).

SEQUENCE: H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH
(Cys10 and 26 bridge)

ONE-LETTER SEQUENCE: SPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH (C10&C26 bridge)

MOLECULAR FORMULA: C₁₄₃H₂₄₄N₅₀O₄₂S₄

MOLECULAR WEIGHT: 3464.09

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [114471-18-0]

SYNONYMS: Brain Natriuretic Peptide-32 (human), Nesiritide, BNP-32 (human)

RESEARCH AREA: Cardiovascular

REFERENCES:
T. Sudoh et al., BBRC, 159, 1427 (1989)

SKU(s): NATR-009A, NATR-009B, NATR-009C

KEYWORDS: hormone