Description

A superagonist with ultraprolonged melanotropic activity in frog and lizard skin bioassays. It exhibits a complete resistance to tryptic degradation.

SEQUENCE: Ac-Cys-Glu-His-DPhe-Arg-Trp-Cys-Lys-Pro-Val-NH2 (trifluoroacetate salt)
(Cys1 and 7 bridge)

ONE-LETTER SEQUENCE: Ac-CEH-DPhe-RWCKPV-NH2 (Cys1 and 7 bridge)

MOLECULAR FORMULA: C₆₁H₈₆N₁₈O₁₃S₂

MOLECULAR WEIGHT: 1343.6

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [91050-39-4]

SYNONYMS: melanotropins, AC-CEHFRWCKPV-NH2;[Ac-Cys4, D-Phe7, Cys10]-α-MSH (4-13);(AC-CYS4,D-PHE7,CYS10)-ALPHA-MSH (4-13);Acetyl-(Cys4,D-Phe7,Cys10)-a-MSH (4-13);Acetyl-(Cys4,D-Phe7,Cys10)-α-MSH (4-13);[Ac-Cys4,DPhe7,Cys10] a-MSH (4-13), amide;2:PN:WO2013067309 SEQID:102 claimed protein;[ACETYL-CYS4, D-PHE7, CYS10]-ALPHA-MSH (4-13);AC-CYS-GLU-HIS-D-PHE-ARG-TRP-CYS-LYS-PRO-VAL-NH2;[AC-CYS4, D-PHE7, CYS10]-ALPHA-MSH (4-13), AMIDE

RESEARCH AREA: Hormonal

REFERENCES:
W.L. Cody et al., J. Med. Chem., 28, 683 (1985)

SKU(s): MSHS-005A, MSHS-005B

KEYWORDS: hormone