Description

Motilin analog that produce an stimulating response in the chicken gastrointestinal tract with a different sensitivity from region to region. It contracts the intestinal segments by direct action on the smooth muscle cells but it causes contraction and enhancement of electrical field stimulation-induced response through an action on the intramural cholinergic neurons.

SEQUENCE: H-Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: FVPIFTYGELQRLQEKERNKGQ

MOLECULAR FORMULA: C₁₂₁H₁₉₀N₃₄O₃₅

MOLECULAR WEIGHT: 2681.1

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [116283-54-6]

SYNONYMS:

RESEARCH AREA: Gastrointestinal

REFERENCES:
E. Miyashita et al., Biotechnology Letters, 10, 763 (1988)

SKU(s): MOTI-002A, MOTI-002B

KEYWORDS: hormone