Description
Intestinal peptide that stimulates contraction of gut smooth muscle. The motilin receptor has not been cloned yet, but motilin-receptor agonists appear to be potent prokinetic agents for the treatment of dysmotility disorders.
SEQUENCE: H-Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Met-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln-OH (trifluoroacetate salt)
ONE-LETTER SEQUENCE: FVPIFTYGELQRMQEKERNKGQ
MOLECULAR FORMULA: C120H188N34O35S1
MOLECULAR WEIGHT: 2699.09
STORAGE CONDITIONS: -20 ± 5 °C
CAS REGISTRY NUMBER: [9072-41-7]
SYNONYMS:
RESEARCH AREA: Gastrointestinal
REFERENCES:
P. de Clercq et al., Regul. Peptides, 55, 79 (1995)
SKU(s): MOTI-001A, MOTI-001B
KEYWORDS: hormone
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