Description

Inhibitor of human matrix metalloproteinases that maintains its activity even after prolonging incubation with pronase or human granulocyte elastase. It also inhibits interstitial and granulocyte collagenases, granulocyte gelatinase and skin fibroblast stromelysin with IC50 of 1 x 10^-6 M, 3 x 10^-5 M and 1.5 x 10^-4 M, respectively.

SEQUENCE: H-Abz-Gly-Pro-DLeu-DAla-NH-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Abz-GP-DLeu-DAla-NH-OH

MOLECULAR FORMULA: C₂₃H₃₅N₆O₆

MOLECULAR WEIGHT: 490.55

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [124168-73-6]

SYNONYMS: 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH

RESEARCH AREA: Cancer

REFERENCES:
S. Odake, et al., Biochem. Biophys. Res. Commun. 199, 1442 (1994)

SKU(s): MMPS-001A, MMPS-001B

KEYWORDS: dye-labeled