Description

The peptide IRRP1 is derived from a consensus IFN-alpha sequence and corresponds to a putative receptor recognition domain of IFN-alpha. The binding capacity of cells for IFN-alphas was increased in the presence of IRRP1. Increased receptor occupancy resulted in increased phosphorylation-activation of the transcription factor ISGF3 and enhanced antiviral activity.

SEQUENCE: H-Cys-Leu-Lys-Asp-Arg-His-Asp-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: CLKDRHD

MOLECULAR FORMULA: C₃₅H₅₉N₁₃O₁₂S₁

MOLECULAR WEIGHT: 886

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [153840-64-3]

SYNONYMS:

RESEARCH AREA: Miscellaneous

REFERENCES:
E.N.Fish, FEBS Lett., 365, 87 (1995)

SKU(s): LYMK-001A, LYMK-001B

KEYWORDS: