Description

The native peptide PKTPKKAKKL is derived from the histone H1 peptide sequence that is docked in the active site of cyclin-dependent kinase 5. It is an effective CDK5 substrate (Km = 40 µM).

SEQUENCE: H-Pro-Lys-Thr-Pro-Lys-Lys-Ala-Lys-Lys-Leu-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: PKTPKKAKKL

MOLECULAR FORMULA: C₅₃H₉₉N₁₅O₁₂

MOLECULAR WEIGHT: 1138.45

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [164669-07-2]

SYNONYMS:

RESEARCH AREA: Miscellaneous

REFERENCES:

Lew, J. Biochem. 42, 849 (2003)

Sharma, P. et al. J. Biol. Chem. 274, 9600 (1999)

SKU(s): HIST-081A, HIST-081B

KEYWORDS: