Description

The native peptide PKTPKKAKKL is derived from histone H1 peptide sequence that is docked in the active site of cyclin-dependent kinase 5. It is an effective CDK5 substrate (Km = 40 µM).

SEQUENCE: H-Pro-Lys-Thr(PO3H2)-Pro-Lys-Lys-Ala-Lys-Lys-Leu-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: PK-pT-PKKAKKL

MOLECULAR FORMULA:

MOLECULAR WEIGHT: 1218.5

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Miscellaneous

REFERENCES:
Lew, J. Biochem. 42, 849 (2003)
Sharma, P. et al. J. Biol. Chem. 274, 9600 (1999)

SKU(s): HIST-080A

KEYWORDS: phosphorylated