Description

The native peptide ARKRERTYSFGHHA is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 ?M). It also competitively inhibits histone H2B phosphorylation (Ki = 12 ?M) by AKT.

SEQUENCE: H-Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser-Phe-Gly-His-His-Ala-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: ARKRERTYSFGHHA

MOLECULAR FORMULA: C₇₄H₁₁₄N₂₈O₂₀

MOLECULAR WEIGHT: 1715.87

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [324029-01-8]

SYNONYMS:

RESEARCH AREA: Miscellaneous

REFERENCES:
Obata, T. et al. J. Biol. Chem. 275, 36108 (2000) Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999)

SKU(s): HIST-079A, HIST-079B

KEYWORDS: