Description

The native peptide ARKRERTYSFGHHA (29944-1) is a synthetic substrate for AKT/PKB/Rac-protein kinases. Phophorylation is at the Ser site (Km = 3.9 µM). It also competitively inhibits histone H2B phosphorylation (Ki = 12 µM) by AKT.

SEQUENCE: H-Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser(PO3H2)-Phe-Gly-His-His-Ala-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: ARKRERTY-pS-FGHHA

MOLECULAR FORMULA:

MOLECULAR WEIGHT: 1795.9

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: Protein Kinases and Phosphatases

REFERENCES:
Obata, T. et al. J. Biol. Chem. 275, 36108 (2000) Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999).

SKU(s): HIST-078A

KEYWORDS: phosphorylated