Description

This peptide is the N-terminal of H3 histone (1-20). It has nearly identical acetylation efficiency as the H4 peptides. Acetylation of histones is associated with transcription activity, constitutes a post-translational mark recognized by specific chromatin factors, and prevents salt-induced folding of nucleosome arrays in vitro. Multisubunit histone acetyltransferase (HAT) complexes recognize and perform efficient acetylation on nucleosome substrates.

SEQUENCE: H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: ARTKQTARKSTGGKAPRKQL

MOLECULAR FORMULA: C₉₁H₁₆₇N₃₅O₂₇

MOLECULAR WEIGHT: 2183.55

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [380598-30-1]

SYNONYMS: Histone H3 (1-20)

RESEARCH AREA: Miscellaneous

REFERENCES:
Berndsen, C. et al. Biochem. 46, 2091 (2007)

SKU(s): HIST-026A

KEYWORDS: