Description

This peptide is the FRET substrate for assaying histone deacetylase (HDAC) activity. The assay is based on the principle that the peptide is more sensitive to trypsin cleavage after deacetylation.

SEQUENCE: H-Abz-Gly-Ala-Lys(Ac)-Ala-Ala-Dap(DNP)-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: Abz-GAK(Ac)-AA-Dap(Dnp)-NH2

MOLECULAR FORMULA: C₃₅H₄₈N₁₂O₁₂

MOLECULAR WEIGHT: 828.84

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [761443-02-1]

SYNONYMS:

RESEARCH AREA: Miscellaneous

REFERENCES:
B.E.Schultz et al., Biochemistry, 43, 11083 (2004)

SKU(s): HIST-005A, HIST-005B

KEYWORDS: FRET Substrate