Description

GLP-1 (7-37) is a insulinotropic peptide generated from by precursor GLP-1 (1-37) after proteolytic cleavage. It is secreted by the L cells of intestinal mucosa after food ingestion.

SEQUENCE: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH

ONE-LETTER SEQUENCE: HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG

MOLECULAR FORMULA: C₁₅₁H₂₂₈N₄₀O₄₇

MOLECULAR WEIGHT: 3355.7

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [106612-94-6]

SYNONYMS: Preproglucagon (98-128), Insulinotropin acetate salt, Proglucagon (78-108), Glucagon-Like Peptide 1 (7-37), GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat)

RESEARCH AREA: Diabetes

REFERENCES:
A.Wettergren et al., Regul. Peptides, 77, 83 (1998)
A.B.Damholt et al., Endocrinology, 140, 4800 (1999)
J.M.Conlon, Regul. Peptides, 93 3 (2000)
D.J.Drucker, Gut, 50, 428 (2002)
D.J.Drucker, Gastroenterology, 122, 531 (2002)

SKU(s): GLUC-016A, GLUC-016B

KEYWORDS: hormone