Description

A 29 amino acid sequence containing peptide hormone processed from proglucagon that keeps glucose homeostasis in vivo in both animals and humans. It is also believed to be a potential tool in the therapeutic treatment of diabetes.

SEQUENCE: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: HSQGTFTSDYSKYLDSRRAQDFVQWLMNT

MOLECULAR FORMULA: C₁₅₃H₂₂₅N₄₃O₄₉S₁

MOLECULAR WEIGHT: 3482.8

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [16941-32-5]

SYNONYMS: Glucagon (1-29) (human, rat, porcine)

RESEARCH AREA: Diabetes

REFERENCES:
S.Onoue et al., J. Chromatogr. A, 1109, 167 (2006)
G.Jiang and B.B. Zhang, Am. J. Physiol. Endocrinol. Metab., 284, E671 (2003)

SKU(s): GLUC-004A, GLUC-004B

KEYWORDS: hormone