Description

A decamer peptide amide that is a selective galanin GAL2 receptor agonist (IC50 values of 1.76 and 879 nM for GAL2 and GAL1). Indications as an antiepileptogenic agent; prevents full seizures and postkindling increases in hippocampal excitability.

SEQUENCE: H-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2

ONE-LETTER SEQUENCE: WTLNSAGYLL-NH2

MOLECULAR FORMULA: C₅₄H₈₁N₁₃O₁₄

MOLECULAR WEIGHT: 1136.3

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [367518-31-8]

SYNONYMS: AR-M 1896

RESEARCH AREA: Alzheimer’s Disease

REFERENCES:
Liu et al., Proc.Natl.Acad.Sci USA, (2001) 98: 9960.
Mazarati et al., J.Pharmacol.Exp.Ther., (2006) 318:700

SKU(s): GALA-006A, GALA-006B, GALA-006C

KEYWORDS: