Description

Galanin antagonist that causes widespread antagonism to the action of galanin and reversibly blocks the neuronal actions of galanin in a dose-dependent manner. It inhibits the release of acetylcholine, reduces the response to galanin in the hypothalamus, and blocks the effect of galanin on glucose-induced insulin secretion.

SEQUENCE: H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 (trifluoroacetate salt)

ONE-LETTER SEQUENCE: GWTLNSAGYLLGPQQFFGLM-NH2

MOLECULAR FORMULA: C₁₀₄H₁₅₁N₂₅O₂₆S₁

MOLECULAR WEIGHT: 2199.56

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [138579-66-5]

SYNONYMS: Galanin (1-13)-Substance P (5-11) amide, M15

RESEARCH AREA: Alzheimer’s Disease

REFERENCES:

SKU(s): GALA-002A, GALA-002B

KEYWORDS: