Description

C-terminal fragment of the connecting segment 1 (Cs^-1) in human fibronectin. CS-1is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin that contains the Leu-Asp-Val (LDV) motif. This sequence, recognized as a cell adhesion motif, binds to the integrin receptor alpha4beta1 of melanoma cells and T lymphocytes.

SEQUENCE: H-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: EILDVPST

MOLECULAR FORMULA: C₃₈H₆₄N₈O₁₅

MOLECULAR WEIGHT: 872.97

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [136466-51-8]

SYNONYMS: Fibronectin CS-1 Fragment (1978-1985)

RESEARCH AREA: Inflammation

REFERENCES:
E.A. Wayner et al., JCB, 109, 1321 (1989)

SKU(s): FIBN-007A, FIBN-007B

KEYWORDS: