Description

Fibrinogen is a cofactor in platelet activation. This peptide binds to fibrinogen and inhibits the adhesion of platelets to fibrinogen, platelet aggregation and the adhesion of platelets to vitronectin. The peptide has the characteristics expected of a mimic of a glycoprotein IIb/IIIa ligand binding site.

SEQUENCE: H-Glu-His-Ile-Pro-Ala-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: EHIPA

MOLECULAR FORMULA: C₂₅H₃₉N₇O₈

MOLECULAR WEIGHT: 565.63

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [137235-80-4]

SYNONYMS: Fibrinogen Binding Peptide

RESEARCH AREA: Cardiovascular

REFERENCES:
T.K.Gartner and D.B.Taylor, Proc. Soc. Exp. Biol. Med., 198, 649 (1991)

SKU(s): FBP-001A, FBP-001B

KEYWORDS: