Description

SEQUENCE: H-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH (trifluoroacetate salt)

(Cys1 and 29 bridge, Cys3 and 18 bridge, Cys8 and 28 bridge)

ONE-LETTER SEQUENCE: CYCRIPACIAGERRYGTCIYQGRLWAFCC (C1&C29 bridge, C3&C18 bridge, C8&C28 bridge)

MOLECULAR FORMULA: C₁₄₇H₂₁₇N₄₃O₃₇S₆

MOLECULAR WEIGHT: 3370.95

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [99287-07-7]

SYNONYMS: α-Defensin-2 (Human), alpha-Defensin-2 (Human), Defensin HNP-2 human

RESEARCH AREA: Antimicrobial

REFERENCES:
M.E. Selsted, S.S.L. Harwig, T. Ganz, J.W. Schilling, and R.I. Lehrer, J. Clin. Invest., 76,1436 (1985). (Original)
T. Ganz, M.E. Selsted, D. Szklarek, S.S.L. Harwig, K. Daher, D.F. Bainton, and R.I. Lehrer, J. Clin. Invest., 76,1427 (1985).(First Isolation)
F.T. Lundy, D.F. Orr, C. Shaw, P.-J. Lamey, and G.J. Linden, Oral Oncol., 40, 139 (2004).
C.B. Buck, P.M. Day, C.D. Thompson, J. Lubkowski, W. Lu, D.R. Lowy, and J.T. Schiller, Proc. Natl. Acad. Sci., U.S.A., 103, 1516 (2006).

SKU(s): DEFS-001A, DEFS-001B

KEYWORDS: