Description

CRF antagonist, lyophilized solid that acts as a potent antagonist to CRF receptors to block the behavioral and physiological responses to a stressor when administered in the CNS.

SEQUENCE: H-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2

ONE-LETTER SEQUENCE: DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2

MOLECULAR FORMULA: C₁₆₆H₂₇₄N₄₆O₅₃S₂

MOLECULAR WEIGHT: 3826.41

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [99658-03-4]

SYNONYMS: α-Helical CRF (9-41)

RESEARCH AREA: Hormonal

REFERENCES:
J. Rivier et al., Science, 224, 889 (1984)

SKU(s): CRFS-004A, CRFS-004B

KEYWORDS: hormone