Description

This C-peptide measurement can sensitively assess beta-cell functions under standardized conditions, which is the most suitable primary outcome for clinical trials of therapies aimed at preserving or improving preserving endogenous insulin secretion in type 1 diabetes patients.

SEQUENCE: H-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ

MOLECULAR FORMULA: C₁₂₉H₂₁₁N₃₅O₄₈

MOLECULAR WEIGHT: 3020.3

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [33017-11-7]

SYNONYMS:

RESEARCH AREA: Diabetes

REFERENCES:
A.S.C. Ko and D.G. Smyth, Eur. J. Biochem., 20, 190 (1971)
P.E. Oyer et al., J. Biol. Chem., 246, 1375 (1971)
K. Igano et al., Bull. Chem. Soc. Jpn., 54, 3088 (1981)

SKU(s): CPEP-001A, CPEP-001B

KEYWORDS: