UCI-1 (University of California, Irvine Coronavirus Inhibitor-1)

UCI-1 (University of California, Irvine Coronavirus Inhibitor-1)

Product Number: COVD-009

Sequence:

cyclo[-Phe-Gln-Ser-Lys-AEPA]

Description

UCI-1 (University of California, Irvine Coronavirus Inhibitor-1) is a first-in-class cyclic peptide that inhibits SARS-CoV main protease (Mpro, also known as 3CLpro). UCI-1 was developed by Professor James S. Nowick and designed to mimic the autolytic cleavage site of SARS-CoV Mpro.

SEQUENCE: cyclo(-Phe-Gln-Ser-Lys-AEPA)

ONE-LETTER SEQUENCE: cyclo(-FQSK-AEPA)

MOLECULAR FORMULA: C33H45N7O7

MOLECULAR WEIGHT: 651.77

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER:

SYNONYMS:

RESEARCH AREA: COVID-19 Related Peptides

REFERENCES:
Kreutzer, Adam G., Maj Krumberger, Chelsea Marie T. Parrocha, Michael A. Morris, Gretchen Guaglianone, and James S. Nowick. BioRxiv (2020).

SKU(s): COVD-009

KEYWORDS: lactam