Description

This biotinylated apopain inhibitor has successfully been used for the affinity purification, on a streptavidin-agarose column, of caspase-3 (apopain); the enzyme that cleaves the poly(ADP-ribose) polymerase (PARP). This inhibitor showed an inhibitory act

SEQUENCE: Biotin-Asp-Glu-Val-Asp-CHO

ONE-LETTER SEQUENCE: Biotin-DEVD-CHO

MOLECULAR FORMULA: C₂₈H₄₂N₆O₁₂S₁

MOLECULAR WEIGHT: 686.7

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [178603-73-1]

SYNONYMS:

RESEARCH AREA: Apoptosis

REFERENCES:
D.W. Nicholson et al., Nature, 376, 37 (1995)

SKU(s): CASP-058A

KEYWORDS: