Description

Atriopeptin is synthesized primarily in cardiac atria, acts in opposition to angiotensin II. When blood volume overload, Atriopeptin is released to act at the nephron to increase salt and water excretion, lowering blood volume and blood pressure.

SEQUENCE: H-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-OH (trifluoroacetate salt)
(Cys Bridge)

ONE-LETTER SEQUENCE: SSCFGGRIDRIGAQSGLGCNS(Cys&Cys bridge)

MOLECULAR FORMULA: C₈₃H₁₃₅N₂₉O₃₀S₂

MOLECULAR WEIGHT: 2083.29

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [89139-53-7]

SYNONYMS:

RESEARCH AREA: Cardiovascular

REFERENCES:
M.G.Currie et al., Science, 223, 67 (1984)

SKU(s): ATPE-001A, ATPE-001B

KEYWORDS: hormone