Description

Urumin is a host defense peptide isolated from the skin of the South Indian frog that shows antiviral activity (virucide) for H1 hemagglutinin-bearing human influenza A viruses. The peptide, that shows no homology to known peptide families, targets the H1 hemagglutinin protein of the conserved stalk region.

SEQUENCE: H-Ile-Pro-Leu-Arg-Gly-Ala-Phe-Ile-Asn-Gly-Arg-Trp-Asp-Ser-Gln-Cys-His-Arg-Phe-Ser-Asn-Gly-Ala-Ile-Ala-Cys-Ala-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: IPLRGAFINGRWDSQCHRFSNGAIACA

MOLECULAR FORMULA: C₁₂₉H₁₉₈N₄₂O₃₅S₂

MOLECULAR WEIGHT: 2961.35

STORAGE CONDITIONS: -20 ± 5 °C

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RESEARCH AREA: Antimicrobial

REFERENCES:
Holthausen, David J., et al. “An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses.” Immunity 46 (2017): 587-595.

SKU(s): ATMP-009A, ATMP-009B

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