Description

Activated protein C (APC), proteolyticly inactivate the coagulation cofactors Va and VIIIa. Human APC residues 390-404 are essential for its anticoagulant activity.

SEQUENCE: H-Tyr-Gly-Val-Tyr-Thr-Lys-Val-Ser-Arg-Tyr-Leu-Asp-Trp-Ile-His-OH (trifluoroacetate salt)

ONE-LETTER SEQUENCE: YGVYTKVSRYLDWIH

MOLECULAR FORMULA: C₉₁H₁₃₀N₂₂O₂₃

MOLECULAR WEIGHT: 1900.17

STORAGE CONDITIONS: -20 ± 5 °C

CAS REGISTRY NUMBER: [146340-20-7]

SYNONYMS:

RESEARCH AREA: Cardiovascular

REFERENCES:
R.M.Mesters et al., J. Biol. Chem., 266, 24514 (1991)

SKU(s): ACP-002A, ACP-002B

KEYWORDS: