Peptide & Oligo CDMO Services

Research Peptides

CPC Scientific is one of the premier custom peptide producers in the world and we are proud to offer consistently reliable, high-quality peptides directly to researchers.

GMP Peptides

Large-scale manufacturing capacity to support your GMP projects at every stage, from early discovery and late-phase development to full commercialization.

Oligonucleotides

We provide research-grade and clinical-grade oligonucleotide manufacturing services to our clients spanning from discovery to clinical phases.

Peptide-Oligo Conjugates

Our peptide-oligonucleotide conjugate (POC) services seamlessly integrate our peptide and oligonucleotide platforms.

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Recent Publications and Citations

  • Clairfeuille, T., Buchholz, K.R., Li, Q., Verschueren, E., Liu, P., Sangaraju, D., Park, S., Noland, C.L., Storek, K.M., Nickerson, N.N. and Martin, L. Nature 584, no. 7821 (2020): 479-483.

    • Departments of Structural Biology, Infectious Diseases, Microchemistry, Proteomics & Lipidomics, Drug Metabolism & Pharmacokinetics, Translational Immunology, BioMolecular Resources, Biochemical & Cellular Pharmacology, Bioinformatics & Computational Biology, Discovery Chemistry Departments, Genentech Inc., South San Francisco, CA, USA.

    LAB peptides ([..], CPC Scientific, [..] l, standard solid-phase peptide synthesis) at 10 mM in 50 mM Tris, pH 8, and 100 mM NaCl were diluted in MHB II cation adjusted broth (800 μM top concentration) or LB. Where indicated, EDTA was added to a final concentration of 0.5 mM.

    Published On: August 12th, 2020Categories: Citations
  • Chan, Leslie W., Melodi N. Anahtar, Ta-Hsuan Ong, Kelsey E. Hern, Roderick R. Kunz, and Sangeeta N. Bhatia. Nature Nanotechnology (2020): 1-9.

    HFA-modifed peptides were synthesized by CPC Scientifc (>95% purity). Briefy, the peptide substrate, Ac-CKKK(Cy5)-PEG4-Nle(O-Bzl)-Met(O)2-Oic-Abu-OH, was synthesized on Fmoc-Abu-CTC resin via standard Fmoc solid phase peptide synthesis.

    Published On: July 20th, 2020Categories: Citations, Dye-Labeled, PEGylation, Unnatural Amino Acids
  • Bueno, A.B., Sun, B., Willard, F.S., Feng, D., Ho, J.D., Wainscott, D.B., Showalter, A.D., Vieth, M., Chen, Q., Stutsman, C. and Chau, B. Nature Chemical Biology 16, no. 10 (2020): 1105-1110.

    1. Lilly, S.A., Alcobendas, Spain.
    2. ConfometRx, Santa Clara, CA, USA.
    3. Departments of Quantitative Biology, Discovery Chemistry Research and Technologies, and Diabetes and Complications, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN, USA.
    4. Lilly Biotechnology Center San Diego, San Diego, CA, USA.

    Peptides were synthesized and purified to >95% purity at Eli Lilly and Company or purchased from CPC Scientific or Tocris. GLP-1(9-36)NH2, GLP-1(7-36)NH2, OXM(1-37)OH and GIP(1-42)NH2 were used for pharmacology experiments, and GLP-1(7-37)OH was used for cryo-EM studies.

    Published On: July 20th, 2020Categories: Citations

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(HKEX: 03880)
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