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      1. Home
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      3. Citations

      Citations Archive

      • Ionic liquid-mediated transdermal delivery of thrombosis-detecting nanosensors.

        Bekdemir, Ahmet, Eden EL Tanner, Jesse Kirkpatrick, Ava P. Soleimany, Samir Mitragotri, and Sangeeta N. Bhatia Advanced Healthcare Materials (2022): 2102685.

        Peptides [TDN-qFAM, C-(PEG)2-K(CPQ2)-GGGSRPfGG-5FAM] were obtained from Tufts University Peptide Core Facility or CPC Scientific, Inc (USA)

        Published On: March 14th, 2022Categories: Citations, D-Amino Acids, Dye-Labeled, FRET Substrates, PEGylation
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      • Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensors.

        Mac, Quoc D., Anirudh Sivakumar, Hathaichanok Phuengkham, Congmin Xu, James R. Bowen, Fang-Yi Su, Samuel Z. Stentz et al. Nature Biomedical Engineering (2022): 1-15.

        "FITC-labelled GzmB substrate peptides with internal quencher ((5FAM)aIEFDSG(K-CPQ2)kkc) were synthesized by CPC Scientific and used for all in vitro activity assays. [..] Quenched fluorescent peptides for screening candidate substrates ((5FAM)-{substrate}-(K-DABCYL)-amide"

        Published On: March 8th, 2022Categories: Citations, Dye-Labeled, FRET Substrates
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      • Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer.

        Lopez, Andrea, Denis E. Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A. Miranda-Roman, Lars Ulrik Nordstrøm et al. Nature Communications 13, no. 1 (2022): 1-18.

        "Hydrocarbon-stapled peptide corresponding to the BH3 domain of BIM, FITC-BIM SAHBA2: FITC-βAla-EIWIAQELRS5IGDS5F’NAYYA-CONH2, where S5 represents the non-natural amino acid inserted for olefin metathesis, was synthesized, purified at >95% purity by CPC Scientific Inc."

        Published On: March 7th, 2022Categories: Citations, Dye-Labeled, Peptide Macrocycles, Showcase Macrocycles, Stapled Peptides, Unnatural Amino Acids
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      • A Potent Inhibitor of Aminopeptidase P2 Reduces Reperfusion Injury in Models of Myocardial Infarction and Stroke

        Lenz, Morgan R., Shih-Yen Tsai, Anne E. Roessler, Yang Wang, Periannan Sethupathi, W. Keith Jones, Gwendolyn L. Kartje, and William H. Simmons. Journal of Pharmacology and Experimental Therapeutics 380, no. 3 (2022): 220-229.

        "The ST-115 [ [(S)-2-mercapto-4-methylpentanoyl]-4(S)-fluoro-Pro-Pro-3(R)-beta-Pro] preparation used in this study was custom synthesized by CPC Scientific, Inc., (Sunnyvale, CA), a GMP-capable company. The synthetic scheme is detailed in US patent"

        Published On: March 1st, 2022Categories: Citations, Unnatural Amino Acids
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      • Synthetic Antibiotic Derived from Sequences Encrypted in a Protein from Human Plasma

        Cesaro, Angela, Marcelo DT Torres, Rosa Gaglione, Eliana Dell’Olmo, Rocco Di Girolamo, Andrea Bosso, Elio Pizzo et al. ACS Nano 16, no. 2 (2022): 1880-1895.

        Expression and isolation of recombinant peptides were carried out as previously described.20 CATH-2 and (ri)-r(P)ApoBSPro peptides were obtained from CPC Scientific Inc. (Sunnyvale, CA) and CASLO ApS (Kongens Lyngby, Denmark), respectively.

        Published On: February 3rd, 2022Categories: Citations, Cosmetic Peptides
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      • Comprehensive insulin receptor phosphorylation dynamics profiled by mass spectrometry.

        Liao, Z., Zhang, C., Ding, L., Moyers, J.S., Tang, J.X. and Beals, J.M. The FEBS Journal 289, no. 9 (2022): 2657-2671.

        • Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, USA.

        Synthetic peptides of hIR-B were purchased from CPC Scientific..

        Published On: November 26th, 2021Categories: Citations
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      • Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors.

        Cazanave, S.C., Warren, A.D., Pacula, M., Touti, F., Zagorska, A., Gural, N., Huang, E.K., Sherman, S., Cheema, M., Ibarra, S. and Bates, J. Science Translational Medicine 13, no. 616 (2021): eabe8939.

        All peptides were synthesized by CPC Scientific Inc. For fluorogenic assays, peptides were flanked with the fluorophore-quencher pair 5-FAM-CPQ2. For in vivo urine experiments, peptides were barcoded with Glu-Fib–derived and heavy isotope–labeled peptides. PEGylated peptides were pooled prepared before in vivo experiments and stored at 4°C in phosphate-buffered saline.

        Published On: October 20th, 2021Categories: Citations, Dye-Labeled, FRET Substrates
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      • Inhibition of Escherichia coli lipoprotein diacylglyceryl transferase is insensitive to resistance caused by deletion of Braun’s lipoprotein.

        Diao, J., Komura, R., Sano, T., Pantua, H., Storek, K.M., Inaba, H., Ogawa, H., Noland, C.L., Peng, Y., Gloor, S.L. and Yan, D. Journal of Bacteriology 203, no. 13 (2021): 10-1128.

        • Departments of Infectious Diseases, Structural Biology, Biochemical and Cellular Pharmacology, Translational Immunology, Pathology, Protein Chemistry, Early Discovery Biochemistry, Genentech, South San Francisco, California, USA

        For the Lgt biochemical assay, the Pal-IAAC and Pal-IAAA peptides were synthesized by CPC Scientific.

        Published On: June 8th, 2021Categories: Citations, Lipidation
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      • Pharmacokinetics and safety of TCMCB07, a melanocortin-4 antagonist peptide in dogs.

        Axiak-Bechtel, Sandra M., Stacey B. Leach, David G. Scholten, Jessica R. Newton-Northup, Brendan J. Johnson, H. E. Durham, Kenneth A. Gruber, and Michael F. Callahan. Pharmacology Research & Perspectives 9, no. 3 (2021): e00777.

        TCMCB07 [a cyclic substituted melanocortin antagonist with the structure Ac- Nle- cyclo[Asp- Pro- DNal(2’)-Arg- Trp- Lys]- DVal- DPro- NH2] was manufactured by CPC Scientific Inc. under cGMP conditions. Active pharmaceutical ingredient was dissolved in milliQ water at 10 mg ml−1, sterile filtered [..]”

        Published On: May 20th, 2021Categories: Citations, D-Amino Acids, GMP Peptide Manufacturing, Peptide Macrocycles, publications, Showcase Macrocycles, Unnatural Amino Acids
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      • An integrated genomic, proteomic, and immunopeptidomic approach to discover treatment-induced neoantigens.

        Olsson, N., Heberling, M.L., Zhang, L., Jhunjhunwala, S., Phung, Q.T., Lin, S., Anania, V.G., Lill, J.R. and Elias, J.E. Frontiers in Immunology 12 (2021): 662443.

        • Department of Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, CA, United States
        • Department of OMNI Biomarker Development, Genentech, South San Francisco, CA, United States

        In total 30 synthetic peptides covering a total of 22 SNP sites and two potential neoantigens, were purchased from CPC Scientific (Sunnyvale, CA) with a purity of >70%, dissolved in 0.1% FA and quality checked at a concentration of 250 fmol by mass spectrometry.

        Published On: April 14th, 2021Categories: Citations
        Learn More
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