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      1. Home
      2. Posts
      3. Jen Lee

      Jen Lee Archive

      • Ensuring Quality & Scale in GMP Peptide & Oligonucleotide API Manufacturing

        In today’s biotech landscape, quality is essential. For therapeutics based on peptides or oligonucleotides, many of which treat complex or life-threatening conditions, GMP compliance is a foundational element of regulatory approval and patient trust.

        Published On: October 22nd, 2025Categories: Articles
        Learn More
      • How Our FTE Model Enables Flexible, Cost-Efficient Peptide Manufacturing Support

        At CPC Scientific, we know that peptide programs rarely move in a straight line. That’s why our FTE services are designed to provide dedicated scientific support, supplementing your team with our CRDMO manufacturing expertise and facilities...

        Published On: October 15th, 2025Categories: Articles
        Learn More
      • What is a CDMO, and How Does Partnering With One Accelerate Your Programs?

        Selecting the right partner can directly impact both speed-to-market and long-term commercial success, particularly for peptide and oligo programs. A CDMO addresses this by providing support across the drug development lifecycle.

        Published On: October 7th, 2025Categories: Articles
        Learn More
      • Emerging Uses & Technical Hurdles of Peptide–Oligonucleotide Conjugates

        Peptide–oligo conjugates are innovative hybrid molecules uniting the targeting precision of peptides with the gene-modulating power of oligos. However, harnessing their potential requires overcoming significant technical barriers...

        Published On: September 24th, 2025Categories: Articles, Peptide-Oligonucleotide Conjugates
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      • BPS 2025 Highlights: Showcasing Breakthroughs in Large-Scale Peptide Manufacturing

        CPC Scientific is back at Boulder Peptide Symposium 2025 as a Gold Sponsor! Discover key moments from the symposium and see how our team is pioneering innovations in large-scale synthesis as a leading peptide manufacturer...

        Published On: September 17th, 2025Categories: Articles
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      • Behind the Science: Baosheng Liu, PhD on Turning Innovation into Scalable Solutions

        We recently caught up with Chief Solutions Officer Baosheng Liu, PhD to discuss how CPC Scientific is shaping the future of peptide and oligo manufacturing, and how the CDMO industry is evolving in the next decade...

        Published On: September 10th, 2025Categories: Articles
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      • Peptides in the Air: Advancing Respiratory Disease Diagnosis Through Breath Analysis

        A hot trend in the diagnostic field is the development of noninvasive peptide biosensors for real-time disease detection. The use of engineered peptide substrates to detect protease activity in human breath is a novel diagnostic strategy...

        Published On: July 31st, 2025Categories: Articles
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      • A breath-based in vitro diagnostic assay for the detection of lower respiratory tract infections

        Chen, D., Mirski, M. A., Chen, S., Bryden, W. A., McLoughlin, M., Kiser, K. M., Caton, E. R., Haddaway, C. R., Cetta, M. S., & Pan, Y. PNAS nexus (2024), 3(9).

        PEG36-Nle(O-Bzl)-Met(O)2-Oic-Abu-ACC was designed in house and synthesized by CPC Scientific Inc (San Jose, CA, Fig. S1). Amino-PEG36-acid (CAS: 196936-04-6) and 2-(7-amino-2-oxochromen-4-yl)acetamide (CAS:296236-23-2) were used for the synthesis. The synthesized sensor was resuspended in high-performance liquid chromatography (HPLC)-grade water with a concentration of 200 µM.

        Published On: July 23rd, 2025Categories: Citations, PEGylation
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      • Nanobody-Targeted Conditional Antimicrobial Therapeutics

        Chayanon Ngambenjawong, Henry Ko, Tahoura Samad, Novalia Pishesha, Hidde L. Ploegh, and Sangeeta N. Bhatia. ACS Nano 2025 19 (10), 9958-9970.

        Therapeutic peptides and their Cy7-labeled analogs (Table S1 and Figure S14) were synthesized by CPC Scientific (CA, U.S.A.) via standard Fmoc-based SPPS.

        Published On: July 23rd, 2025Categories: Citations, Dye-Labeled
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      • Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca dependent allosteric binding site

        Dakin, L.A., Xing, L., Hall, J. et al. Nat Commun 16, 4579 (2025).

        The enzymatic reaction was started with the addition of 8 µM of substrate Atto655 - (Ser-Arg-Gly-Ala)3 (CPC Scientific Inc.) in assay buffer.

        Published On: July 23rd, 2025Categories: Citations, Dye-Labeled
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